Cancerstemcells相关论文
Background::Despite improvements in disease diagnosis, treatment, and prognosis, breast cancer is still a leading cause ......
Interferon-gamma inhibits aldehyde dehydrogenasebright cancer stem cells in the 4T1 mouse model of b
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Side population cells isolated from KATO Ⅲ human gastric cancer cell line have cancer stem cell-like
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The discovery of cancer stem cells (CSCs) has changed the applicability of chemotherapy[1].CSCs evade the anti-cancer ef......
Oligosaccharides of hyaluronan conjugates-based dual pH-responsive nano-pupa for cancer stem cell ta
Recently,novel pH-responsive nanoscale drug delivery systems (NDDS) were constructed for cancer therapy[1,2].However,owi......
Thermo-sensitive liposomes tri-loaded with doxorubicin,vincristine,and salinomycin for co-inhibition
Cancer stem cells (CSCs) have been studied as a target for overcoming drug resistance which plays an important role in t......
Elimination of Quiescent Slow-Cycling Cells via Reducing Quiescence Depth by Natural Compounds Purif
The medical mushroom Ganoderma lucidumhas long been used and shown effective in Traditional Chinese Medicine for the tre......
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Enhanced expression of PKM2 associates with the biological properties of cancer stem cells from A549
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Objective Background: Breast cancer is the most commonly diagnosed female cancer and the 6th leading cause of cancer-rel......
Inhibitory effect of epirubicin-loaded lipid microbubbles bound with anti-ABCG2 antibody combined wi
To investigate the inhibitory effect of epirubicin (EPI)-loaded lipid microbubbles (MBs) bound with anti-ABCG2 monoclona......
Objective Metastatic breast cancer may be resistant to chemo-immunotherapy due to the existence of cancer stem cells(CSC......
Emerging evidence indicates that dysregulated long non-coding RNA (lncRNA) HOTAIR correlates highly with tumor invasion ......
Human epithelial ovarian cancer cells expressing CD105,CD44 and CD106 surface markers exhibit increa
Objective The high rate of mortality associated with ovarian cancer(OC)is due in part to the development of resistance t......
Biological impact of transforming growth factor β2 on the proliferation of gastric cancer stem cells
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TCF4 promotes tumor growth and metastasis in gastric cancer through upregulation of self-renewal cap
Tumor resistance and recurrence following treatment remains a major clinical challenge.Basic or clinical evidence indica......
Evaluation of characteristic of CD117+CD44+ovarian cancer stem cells in three dimensional basement m
Background: Cancer stem cells (CSCs) are thought to be able to survive conventional chemotherapeutic treatments because ......
miR-125b Attenuates Epithelial-Mesenchymal Transitions and Targets Stem-Like Liver Cancer Cells thro
Most HCC patients die from metastasis and recurrence.Emerging evidence suggests that EMT contributes to the promotion of......
mTOR Signaling Activation in Immature Cells of Primary Nasopharyngeal Carcinoma and Anti-Tumor Effec
mTOR signaling is a key pathway in the progression of different cancers and the homeostasis of stem cell.Here,we investi......
Cancer stem ceils (CSCs) have been defined as a unique subpopulation in tumors that possess the ability to initiate tumo......
Targeting STAT3 in Head Neck Squamous Cell Carcinoma:From Fundamental Research to Drug Delivery Syst
Objective: Head and neck squamous cell carcinoma(HNSCC)affects 600,000 new patients each year and accounts for over 90%o......
Backgroud:Breast cancer stem cells are a subpopulation of tumor cells with the capacity of self-renew and differentiate ......
Objective: To investigate the characteristics of breast cancer stem cells and their protein expression of RecQ family he......
Afatinib enhances the efficacy of conventional chemotherapeutic agents by eradicating cancer stem-li
Background Cancer stem cells (CSC) have garnered significant attention as a therapeutic focus, based on evidence that th......
miR-125b Attenuates Epithelial-Mesenchymal Transitions and Targets Stem-Like Liver Cancer Cells thro
BACKGROUND & AIMS: Most hepatocellular carcinoma (HCC) patients die from metastasis and recurrence.Emerging evidence sug......
MiR-21 down-regulation mediates Glioblastoma Cancer Stem Cells Proliferation and Apoptosis by target
Objectives: To investigate whether the miR-21 could down-regulate FASLG to regulate the proliferation and apoptosis in g......
Thymosin alphal enhanced cytotoxicity of iNKT cells against colon cancer via upregulating CD1d expre
Aim Thymosin-alphal (TA), used as an immune modulator in clinics, has limited studies about its effect on cancer cells.H......
Afatinib enhances the efficacy of conventional chemotherapeutic agents by eradicating cancer stem-li
Cancer stem-like cells (CSC) have garnered significant attention as a therapeutic focus, based on evidence they may repr......
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Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem c
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Identification of a stringent subtype of tumorigenic side population from hepatocellular carcinoma c
Objective: To identify a more consistent and homogeneous tumorigenic side population (SP) from hepatocellular carcinoma ......
Recognition and killing of cancer stem-like cell population in hepatocellular carcinoma cells by cyt
There is an urgent need for more potent and safer approaches to eradicate cancer stem cells (CSCs) for curing cancer.In ......
Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma vi
Cancer stem cells (CSCs) are considered to be the root cause for cancer treatment failure.Thus,there remains an urgent n......
Cellular Targets Identification and Lead Optimization of Natural Small-Molecule STAT3 Inhibitors Tar
Signal transducer and activator of transcription 3(STAT3) is an oncogene constitutively activated in many human cancers[......
The stemness of different side population(SP)cell subtypes in ovarian cancer cells was studied,and the heterogeneity of ......
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目的探讨微管相关蛋白轻链3-Ⅱ(LC3Ⅱ)与白细胞分化抗原44(CD44)在结直肠癌及其浸润性成分中的表达，分析两者在结直肠癌发生发展及......
Efficacy of the new therapeutic approach in curing malignant neoplasms on the model of human gliobla
Objective: Glioma is a highly invasive tumor, frequently disposed in essential areas of the brain, which makes its surgi......
Pancreatic ductal adenocarcinoma (PDAC) has one of the highest mortality rates among all cancer types. Its delayed diagn......
The capacity of pluri-potent stem cells to repair the tissues in which stem cells reside holds great promise in developm......
目的:探讨过表达Twist1对结直肠癌SW620细胞多药耐药性(MDR)的影响及其可能的机制.方法:利用过表达Twist1的慢病毒和阴性对照病毒......
盐霉素作为一种提取自白色链霉菌的离子载体型抗生素,具有抑制肿瘤细胞及干细胞生长、增殖及转移的作用,甚至可导致细胞凋亡.近些......
目前已在多种肿瘤中发现了肿瘤干细胞（ CSCs）存在的证据，CSCs在肿瘤的耐药、转移复发过程中发挥关键作用。 CD133已作为CSCs标识广泛......
近年来,对肿瘤干细胞巢的深入研究开启了肿瘤研究的“巢”时代,结直肠癌是实体肿瘤的典型代表,有较为典型的发生发展机制,是肿瘤干......
Recent studies on cancer stem cells (CSCs), a special subpopulation of tumor cells, promote our understanding of tumorig......
